Excess potassium in the blood is a common condition in chronic renal failure and is potentially life-threatening. The action of the functional polymer is simple ion exchange; the polymer is in the sodium form and the sodium ions are exchanged with the excess potassium in the blood stream as the resin passes through the GI tract. Typical dosage amounts are 15-60 g per day for extended periods of time. Formulations are either powder sachets or aqueous suspensions.
HYPERCHOLESTEROLEMIA :
Cholestyramine Resin USP DUOLITE™ AP143 grades
Elevated levels of cholesterol is known to be an important factor in likelihood of cardiac arrests. Cholesterol is known to be a key intermediate in the biosynthesis of bile acids which are present in the GI tract. These bile acids can be bound to an anionic exchange resin and so effectively removing them from the body. This leads to replenishment of the bile acids through increased metabolism of cholesterol resulting in lowered serum cholesterol levels. Typical dosage amounts are 8-24g per day for extended periods. A number of different formulations are commercialised although the predominant one is a powder sachet or small container.
References : Actives
